Henry Fonda as Frank Comments

Gotta have a Western villain on this list. He could be Jack
Palance's stirrup-ringing sadist from Shane or Henry
Brandon's Comanche chief from The Searchers. But we'll go
with Fonda, who possessed one of the movies' naturally
heroic faces and was turned niftily against type to play a
gunman for hire in this Sergio Leone epic. Robert Osborne of
Turner Classic Movies notes that Fonda showed up on the set
with a beard and brown contact lenses, so he'd look more
villainous; Leone said no, you should look just as you
always have — just be evil. So the smile turned into a
scowl, and Fonda the torturer of good men and children came
blazingly to life.